- Top Pick
- Comparison Table
- Renue by Science
- What is NMN
- Benefits of NMN
Nicotinamide Mononucleotide (NMN) supplements are gaining popularity in health and wellness for their potential anti-aging and energy-boosting benefits. NMN, a niacin (Vitamin B3) derivative, is crucial for cellular metabolism and energy production. With aging, our NMN levels naturally decrease, leading to age-related issues. NMN supplements promise to mitigate or reverse some aging effects.
The market offers numerous NMN supplements, each claiming to be the best, which complicates the selection process. The main aim of NMN supplementation is to increase Nicotinamide Adenine Dinucleotide (NAD+) levels, a coenzyme vital for mitochondrial health, DNA repair, and sirtuin activation, all critical for aging and health. NMN supplements are designed to boost NAD+ levels, offering potential anti-aging and metabolic benefits.
The effectiveness of NMN supplements varies based on factors like purity, absorption rate, and delivery method. For example, liposomal delivery enhances bioavailability, ensuring more NMN reaches the necessary cells. The NMN source, manufacturing, and added ingredients also determine supplement quality.
As we navigate through this guide, we'll provide insights into the scientific basis behind NMN supplementation, discuss the key factors to consider when selecting a product and give our recommendation for the best NMN supplement.
Our Top Pick
GenuinePurity Liposomal NMN stands out in the crowded field of NMN supplements due to its advanced liposomal delivery system, unparalleled purity, increased bioavailability, positive user experiences, scientific backing, and safety profile. These attributes collectively contribute to its top-ranking status, making it a go-to choice for individuals seeking to enhance their health and combat the effects of aging through NMN supplementation.
Best NMN Supplement Comparison Table
|Editors Choice GenuinePurity Liposomal NMN
|Renue by Science
|Omre NMN + Resveratrol
|Where to buy
|NMN dosage per capsule
|Price per bottle
|Number of capsules
|One capsule a day
|Two capsules a day
|Two capsules a day
|One or two capsules a day
|Two capsules a day
|Two capsules a day
1. GenuinePurity Liposomal NMN
- Manufactured in GMP-certified facilities in USA
- Supported by scientific studies
- Offers a 90-day money back guarantee
- Uses liposomal for better absorption
- High purity and quality standards
- Recognized brand reputation
- No presence of GMOs, eggs, soy, dairy products, sugar, gluten, or preservatives
- Lacks a subscription option
GenuinePurity Liposomal NMN has rapidly gained a leading position in the NMN supplement market, thanks to its unique combination of quality, efficacy, and innovative delivery. Central to its success is the pioneering liposomal delivery system. These microscopic spherical vesicles encapsulate NMN, enhancing its absorption into the bloodstream and maximizing bioavailability. This advanced system is crucial, as it overcomes the common issue of NMN breakdown and loss during digestion, ensuring more efficient delivery to target cells.
The product's purity is another hallmark of its excellence. Each capsule of GenuinePurity contains 250 mg of β-Nicotinamide Mononucleotide. This amount has been clinically studied and shown to boost NAD+. It also undergoes stringent testing and quality control to ensure that it is free from contaminants, a practice that's integral to its brand ethos. This 96% pure NMN, coupled with the effectiveness of its liposomal delivery, not only enhances safety but also significantly improves the supplement's overall efficacy in raising NAD+ levels, which is pivotal for combating aging signs, boosting energy, and supporting cellular health.
Genuine Purity Liposomal NMN is made by LeadingEdgeHealth, a company that has been in the business of making supplements for over 20 years. This extensive experience is reflected in their offering of a whopping 90-day money-back guarantee for Liposomal NMN. You get a 90-day trial period with Liposomal NMN. If you don't feel significantly younger and completely satisfied, you can return the bottles for a complete refund of what you paid.
In terms of safety, GenuinePurity maintains the highest standards. It's manufactured in cGMP-certified facilities, regularly inspected by the FDA, and located in the USA. Regular testing for heavy metals, microbial contaminants, and other hazards ensures a safe user experience.
GenuinePurity Liposomal NMN Pricing
GenuinePurity provides discounts for buying Liposomal NMN in large quantities. You'll find 60 servings in every bottle. To help you understand the potential savings, here's a useful chart.
|Discount price per bottle
Each offer comes with free USA shipping but it only applies to Lower 48 States so no Hawaii, Alaska and Other Territories.
You can get GenuinePurity Liposomal NMN at these discounted prices by visiting their official site through one of our links.
2. Wonderfeel Youngr NMN
- Each capsule has a substantial 450mg of NMN
- Recommended dosage is two capsules in the morning, amounting to 900 mg of NMN
- Verified by independent testing
- Includes four beneficial support ingredients
- Suitable for vegans, gluten-free, and free from GMOs
- Capsules start to dissolve in stomach acid
- More expensive than the majority of products on this list
Wonderfeel Youngr emerges as a noteworthy contender in the NMN supplement landscape. It's designed to cater to those seeking not only anti-aging benefits but also a holistic boost in their overall wellness. The scientist behind their patented NMN is Andrew Salzman MD from Harvard University.
Wonderfeel Youngr's formula is a blend of carefully selected ingredients, each playing a vital role in its effectiveness. The primary component is NMN, which is complemented by a range of other supportive elements. These include antioxidants, vitamins, and minerals that synergistically work to enhance the benefits of NMN. This section delves into the science behind these ingredients and their collective impact on health and aging.
One of the hallmarks of Wonderfeel Youngr is the range of benefits reported by its users. These benefits extend beyond anti-aging to include improved energy levels, enhanced cognitive function, and better overall vitality.
The main concerns we have with Youngr involve the design of its capsules. The capsules are made from rice hulls that break down rapidly in stomach acid, leading to a situation where NMN might lose its effectiveness quickly. Another downside is their return policy. Refunds are available for products bought from their website, provided they are unopened and returned within 30 days of delivery. However, they do not accept returns for items that have been used, opened, or seem to have been tampered with.
Wonderfeel Youngr NMN Pricing
Wonderfeel offers discounts for those who sign up for a subscription. Each bottle contains 60 capsules. To give you a clearer idea of how much you can save, we've provided an easy-to-understand table.
|Price per bottle
|Price per bottle when you subscribe
When ordering for the first time, you will receive a $10 discount on a one-time purchase, making the price $88. However, subsequent purchases will revert to the regular price of $98. For the subscription option, there are also savings. On your first subscription, you will save $10 per bottle, and this discounted price will remain until you cancel the subscription. If you cancel and later decide to subscribe again, the price will then be $83.
3. ProHealth Longevity Liposomal NMN Pro
- Capsules are protected from stomach acid by liposomal coating
- Free delivery on purchases exceeding $30
- Independently verified through third-party testing
- Manufactured in the United States
- Provides a 75-day window for money-back guarantee
ProHealth Longevity Liposomal NMN Pro distinguishes itself in the NMN supplement market with several unique features. Firstly, it's backed by a clinical study, demonstrating a significant 38% increase in NAD+ levels and a notable reversal in biological age. This evidence-based approach assures users of its efficacy in promoting overall wellness.
ProHealth sources its NMN from Uthever, a patented provider known for offering NMN with a purity level exceeding 99%. The supplement uses a liposomal delivery system just like GenuinePurity does for their supplement. This method encapsulates NMN in nano-sized liposomes, ensuring enhanced bioavailability and effective absorption.
ProHealth Longevity Liposomal NMN Pro also boasts a convenient capsule form, tailored for ease of use. This design caters to individuals with active lifestyles, ensuring that maintaining a supplement routine is as hassle-free as possible. The capsule form is particularly user-friendly for those who travel frequently or have busy schedules.
In terms of purity and safety, ProHealth's product excels. It's manufactured in an FDA-registered, GMP-certified facility, ensuring adherence to high-quality manufacturing practices. Furthermore, it's third-party tested in the United States, providing an additional layer of assurance regarding its quality, purity, and potency. The availability of Certificates of Analysis is a testament to its transparency and reliability.
Lastly, ProHealth Longevity Liposomal NMN Pro is distinguished by its commitment to clean, solvent-free production. This approach aligns with the needs of health-conscious consumers seeking supplements free from unnecessary chemicals. Alongside being solvent-free, the supplement is free from common allergens like dairy, egg, gluten, and wheat, making it an inclusive choice for various dietary preferences and requirements.
ProHealth Longevity Liposomal NMN Pro Pricing
Here is ProHealth's pricing presented in an easy-to-understand table.
When you subscribe, the price is reduced by 10%. They also offer free US shipping on orders over $30, and they provide a 75-day money-back guarantee, which is quite impressive.
4. Aeternum NMN
- Advertised as being completely pure NMN
- Available for delivery around the globe
- Verified purity by independent testing
- Maintains at least 99% purity for two years
- Very few details on the product's webpage
- Lack of a subscription
- Capsules start to dissolve in stomach acid
Aeternum gets its name from a Latin word 'aeternum' (eˈter.num or eˈt̪ɛrnum) which means 'forever' or 'eternal'. They distribute their NMN products globally, thanks to having stock locations in the US, UK, Europe, Canada, Australia, and Japan, thereby reaching a broader range of customers.
Each Aeternum bottle contains 60 capsules, each containing 500 mg of NMN. They also sell NMN in powder form if you prefer that to capsules.
They don’t specify where the production of Aeternum NMN capsules occurs, but they do state that each product is third-party certified.
Another thing they claim is that Aeternum NMN is 100% pure and maintains 99% purity for at least two years. However, it's important to remember that even FDA-approved and tested medications usually don't achieve this level of purity, so it's best to take this claim with a grain of salt.
The refund policy is the same as that of Wonderfeel, where you have 30 days to return the product, but it must be unopened and in its original condition.
Aeternum NMN Pricing
The pricing of Aeternum NMN is standard, offering both regular and discounted rates. Unfortunately, there is no mention of free shipping or a money-back guarantee, which is disappointing. Nevertheless, below is a table showing the price per bottle.
5. Renue By Science
- Offers 500 mg of NMN per serving
- Capsules are suitable for vegetarians
- Includes free shipping within the US
- Purity verified by independent third-party testing
- Lacks a money-back guarantee
- Unfavorable return policy
Renue by Science's NMN stands out in the supplement market as an innovative product. It offers similar lipid-based encapsulation for enhanced absorption like its competitor, GenuinePurity Liposomal NMN, but its higher pricing sets it apart. This makes it a less accessible choice for some consumers, despite the same mechanism for improving bioavailability.
The Renue formulation is similar to GenuinePurity, where each capsule contains 250 mg of β-Nicotinamide Mononucleotide and no artificial additives. Difference is in the dosage. With Renue you take 2 capsules so it becomes 500 mg of NMN.
Where Renue truly excels is in the variety of NMN and NR supplements it offers. For example, they have NMN products in forms like sprays, gels, powders, and many more.
Renue By Science offers free shipping, an aspect that appeals to customers. However, its return policy and lack of a money-back guarantee might be concerning for some buyers.
Renue By Science Pricing
Similar to the previous product on this list, Renue also offers a straightforward pricing option. Below is a table displaying the price.
6. Omre NMN + Resveratrol
- Includes BioPerine to boost resveratrol absorption
- Offers a balanced 500mg dose of NMN and resveratrol
- Provides savings through both bulk buying and subscription options
- Independently third-party tested for purity, dosage accuracy, and absence of contaminants
- Comes with a 30-day money-back guarantee
- Requires a minimum of $60 for free shipping
- Limited effectiveness of customer support
- The rice-based capsules may dissolve in stomach acid
Omre NMN + Resveratrol ranks highly among NMN supplements, partly because it incorporates BioPerine, a black pepper extract known to improve the absorption of resveratrol. This product boasts high-quality ingredients, combining 500 mg of 98% pure NMN and resveratrol each, along with 5 mg of BioPerine.
This dietary supplement offers several benefits, such as promoting strong nails, youthful skin, elevated energy levels, increased NAD levels to combat age-related diseases, and improved sleep quality. Omre ensures the quality and purity of its product by having independent labs test each batch. These batches are produced in U.S. facilities adhering to FDA guidelines.
For optimal results, Omre recommends taking two capsules with a meal containing healthy fats each morning. This is advised because resveratrol is better absorbed with fats, and taking NMN supplements on an empty stomach is not recommended.
Omre NMN + Resveratrol Pricing
Omre provides discounts for buying in large quantities or through a subscription for their NMN + Resveratrol product. You'll find each bottle packed with 60 capsules. To help you understand how much you can save, we've included a table below.
When choosing the subscription option, you can pick between 30-, 60-, and 90-day intervals.
What is NMN?
NMN, or nicotinamide mononucleotide, is a naturally occurring molecule made from elements like niacin and ribose. It's a key part of DNA and RNA because it's a nucleotide.
This molecule can turn into nicotinamide adenine dinucleotide (NAD+), which is vital for essential functions in the body, such as fixing DNA. As people get older, their NAD levels drop, which can lead to health issues like cancer, arthritis, diabetes, and mental decline.
To boost NAD, people can exercise regularly, eat fewer calories, and get enough good sleep. Some also take NMN supplements to help their body.
NMN is a building block for NAD. A lot of people use NMN supplements to try to slow aging and protect against mental health problems. These supplements work by raising NAD+ levels, which has several benefits:
- Better brain health and defense against brain diseases
- Improved blood circulation
- Enhanced liver function, aiding liver recovery
- Increased insulin production in the pancreas
- Less inflammation and stronger immune cells
- Prevention of insulin resistance in fat cells
- Reduction in muscle loss
Advantages of Taking NMN Supplements
Nicotinamide mononucleotide, or NMN, is key in making nicotinamide adenine dinucleotide (NAD+), an essential enzyme in all living cells. NMN supplements are known for their role in promoting healthy aging and keeping cells in good condition.
NAD+ is important for processes like turning food into energy, fixing DNA, and helping cells communicate. With age or stress, our NAD+ levels can drop, affecting how our cells work. NMN supplements can help keep these levels up.
Here's what good NMN supplements might do:
NMN might help keep your brain sharp and protect against the mental decline that comes with getting older.
Early research shows NMN could affect the immune system and might reduce aging-related inflammation.
Fighting Age-Related Conditions
Studies suggest NMN might help with age-related issues like heart disease, brain diseases, and metabolic problems.
Longevity and Healthy Aging
Studies have shown that pure NMN supplements could lengthen lifespan and support aging well. More research on humans is needed.
NAD+ is crucial for creating energy in cells. NMN supplements might help with metabolic health by boosting mitochondria, the cell's powerhouses.
Studies show that NMN might improve muscle strength and endurance.
Making More NAD+
NMN helps create NAD+, which can raise NAD+ levels in the body. This is supported by studies.
NAD+ is vital for fixing DNA damage from aging and the environment. NMN can help by increasing NAD+ levels.
If you're thinking of adding an anti-aging supplement like NMN to your routine, pick a high-quality one that's been checked for purity and effectiveness. And it's always wise to talk to a healthcare professional before starting any new supplement.
Frequently Asked Questions
Are there risks with NMN supplements?
Short-term use of NMN supplements doesn't appear to be harmful. However, there's a lack of research on the long-term effects of using NMN and having higher NAD levels. Some evidence suggests that while high NAD levels may combat aging, they could also potentially strengthen cancer cells alongside healthy cells. More studies are needed, especially for individuals with a cancer history or those in recovery, before confidently using NMN.
How do NMN supplements compare to NR?
NMN and nicotinamide riboside (NR) aren't clearly ranked, with each having its benefits. NR must convert to NMN in the body to boost NAD. Recent research indicates that NMN can enter cells more easily than previously thought. NR has been linked to more side effects, such as flushing and stomach issues, compared to NMN.
What dosage of NMN is recommended?
The ideal NMN dosage varies from person to person. Absorption rates can differ based on how NMN is taken. A good approach is to start with a lower dose, like 500mg or less. Consider buying 500mg doses that come in two 250mg pills, and initially take just one pill. This method allows you to test its impact while also being cost-effective.
Do NMN supplements actually work?
Our research and tests indicate that NMN supplements are likely effective in boosting NAD levels in the body. Several studies have noted increased NAD levels, and others link NMN to benefits like better athletic performance, sleep, and blood sugar control. Although there are issues with how well it's absorbed, most NMN supplements should have some positive effect.